By Georges Mathé (auth.), Georges Mathé (eds.)
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Additional info for Aseptic Environments and Cancer Treatment
Isolator, designed and used for rearing of germfree animals  and modified for patient isolation. Personnel remains outside the isolator, handling the patient by means of gloves. Air enters under overpressure through a high efficiency inlet filter, and leaves through a fluid trap or an outlet filter. Items are passed through a lock, which is kept as clean as possible by either ultraviolet lamps, and/or an outward high velocity stream of filtered air, or through a germicidal trap. . Results obtained with this method of isolation with a mechanical barrier between patient and outside world are good [3,4, 17, 18, 19, 28].
Nitrogen mustard - Diminution of toxicity in axenic mice. Science 140, 1400-1401 (1963). 4. WILSON, B. : Survival studies of whole-body x-irradiated gum-free (axenic) mice. Radiat. Res. 20, 477-483 (1963). 5. GRISWOLD, D. , LASTER, W. , SNOW, M. , SCHABEL, F. , SKIPPER, H. : Experimental evaluation of potential anticancer agents. XII. Quantitative drug response of the SA 180, CA 755 and leukemia L 1210 systems to a "standard list" of "active" and "inactive" agents. Cancer Res. 23 (4) Part 2, 271-519 (1963).
J. Med. 44, 234-242 (1968). 10. , AMIEL, J. , SCHLUMBERGER, J. : Acute lymphoblastic leukemia treated with a combination of prednisone, vincristine, and rubidomycin. Value of pathogen-free rooms. Lancet 1967 II, 380-382. 11. MIKELSON, G. , HALBERT, M. , SORENSON, S. : Development of an open isolation system for the care of low resistance hospital patients. August 1968, Final Report Contract PH-43-65-999 NCI, NIH. 12. PREISLER, H. , HENDERSON, E. : Gastrointestinal sterilization procedures in patients with acute leukemia.