Download Breast Cancer: Atlas of Clinical Oncology by Clifford A. Hudis M.D., Larry Norton M.D., David J. PDF

By Clifford A. Hudis M.D., Larry Norton M.D., David J. Winchester, David P., M.D. Winchester

A part of the yankee melanoma Society's acclaimed Atlas of medical Oncology sequence, this quantity bargains knowledgeable assessment of breast melanoma. themes variety from epidemiology and genetics to analysis, administration and reconstruction. Post-treatment care, in addition to male breast melanoma, is usually mentioned.

Key positive aspects: - greater than three hundred colour illustrations, images, and radiographs express tumors as they appear - Discusses the most recent concepts, comparable to image-directed biopsy and sentinel node biopsy - contains contributions from best surgeons, radiation oncologists, scientific oncologists, and gynecologists - observed by way of a CD-ROM with the entire textual content and illustrations of the ebook, in totally searchable PDF documents - pictures should be downloaded for lectures and displays viewers: scholars and practitioners in surgical procedure, oncology, and gynecology, radiation oncology

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Extra resources for Breast Cancer: Atlas of Clinical Oncology

Sample text

101 These results have stimulated the design of a second major breast cancer prevention trial, the Study of Tamoxifen and Raloxifene (STAR) that will compare the toxicity, risks, and benefits of raloxifene with those of tamoxifen. Women enrolled in the study will be randomly assigned to receive either 20 mg of tamoxifen or 60 mg of raloxifene for 5 years, with follow-up planned for an additional 2 years. 102–105 The majority of these drugs are presently in phase I to II clinical trials and have already demonstrated their clinical activity in the management of breast cancer.

Am J Hum Genet 1995;57:1457–62. 18. Struewing JP, Hartge P, Wacholder S, et al. The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. N Engl J Med 1997;336:1401–8. 19. Shattuck-Eidens D, Oliphant A, McClure M, et al. BRCA1 sequence analysis in women at high risk for susceptibility mutations. JAMA 1997; 278:1242–50. 20. Couch FJ, DeShano M, Blackwood MA, et al. BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. N Engl J Med 1997;336:1409–15.

71 The effect of ERT on the risk of breast cancer remains an unresolved question. To date, no prospective, randomized study has been completed, and many of the patterns and inconsistencies demonstrated in the available data are similar to those seen in the published series of OC use and breast cancer. The results of several studies of HRT and breast cancer conducted in the United States and abroad are given in Table 2–3. The relative risk estimates80–85 vary considerably. 3 was Table 2–3. 321 Breast Cancer Risk and Management: Chemoprevention, Surgery, and Surveillance associated with HRT (combined estrogen and progestin) among more than 5,500 women followed up at the Wilford Hall United States Air Force Medical Center.

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