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1991. Engineering Design of the Cardiovascular System of Mammals. Englewood Cliffs, NJ, Prentice-Hall. Duck FA. 1990. Physical Properties of Tissue. San Diego, Academic Press. Kaley G, Altura BM (Eds). Microcirculation, vol I (1977), vol II (1978), vol III (1980). Baltimore, University Park Press. Kessel RG, Kardon RH. 1979. Tissue and Organs—A Text-Atlas of Scanning Electron Microscopy. San Francisco, WH Freeman. Lentner C (Ed). Geigy Scientific Tables, vol 3: Physical Chemistry, Composition of Blood, Hematology and Somatometric Data, 8th ed.
The dendrites provide important and complicated sites of interactions as well as channels of variable effectiveness for excitatory inputs, depending on their position relative to the cell body. Among the best examples are the cells of the medial superior olive in the auditory pathway. These cells have two major dendritic trees extending from opposite poles of the cell body. One receives synaptic inhibitory input from the ipsilateral cochlear nucleus, the other from the contralateral nucleus that normally is an excitatory input.
The action of thyrotropin-releasing hormone (TRH), parathyroid hormone (PTH), and epinephrine is catalyzed by adenyl cyclase, and this can be regarded as the classic reaction. However, there are variant mechanisms. In the phosphatidylinositol-diacylglycerol (DAG)/inositol triphosphate (IP3) system, some surface receptors are coupled through another G-protein to the enzyme phospholipase C which cleaves the membrane phospholipid to form DAG and IP3 or phospholipase D which cleaves phosphatidyl choline to DAG via phosphatidic acid.